Cytotoxic Drug Safety Cabinets (CDSCs) provide the primary barrier against exposure to hazardous aerosols released during the preparation, handling, and dispensing of cytotoxic drugs. Regular testing is essential to ensure these cabinets continue to protect staff and surrounding environments.

Why Testing Is Essential

Without proper testing, CDSCs may expose personnel to dangerous particles that accumulate within filters and mechanical components, or allow contaminants to spread into adjacent work areas.

Testing ensures:

• Personnel protection: Safeguards those working with or maintaining the cabinet

• Environmental safety: Prevents contamination of nearby spaces and staff not involved in drug preparation

When to Test CDSCs

Testing is required at critical points, including:

• Initial commissioning: Before the cabinet is first used

• After relocation: When moved to a new site or room

• Post-maintenance: Following mechanical, electrical, or HEPA filter servicing

• Annual certification: At least every 12 months for ongoing compliance

Compliance test requirements

AG&G Services provides comprehensive certification in accordance with AS 2252.5 (2017). Testing covers both performance and operational safety:

Performance testing

• Air velocity and uniformity in the work zone

• Work zone integrity verification

• HEPA filter installation integrity

• Air classification particle counting (ISO 5)

• Air barrier containment assessment

Operational testing

• Noise level measurement

• Luminance verification

• Alarm checks (where applicable)

• UV radiation intensity (where applicable)

Compliance assured

AG&G Services is NATA-accredited to certify CDSCs to the highest standards, ensuring your cabinets provide effective protection for personnel, environments, and compliance requirements.